Composition and Anti-inflammatory Activity of Essential Oil from Trichodesma afrecanum (Boraginaceae) endemic in South-West of Algeria

Abstract

This present investigation was carried to study chemical composition and anti-inflammatory activities of essential oil of Algerian Trichodesma africanum (L) plants as a new natural source of essential oil. Plant material was collected from wild plant populations of Trichodesma africanum (L) (family Boraginaceae) growing on Gebel Taghit region in Bechar (Algeria). The essential oils obtained by water distillation from aerial parts fraish of Trichodesma africanum (L) yielded 1.6%. Thirty-five constituents representing 99.86% of the Algerian Trichodesma africanum (L) essential oil were identified. The major components of Algerian Trichodesma africanum (L) essential are (2E, 6E)-Farnesol (61.26%), Nonalactone<γ-> (20.28%). Minor component are Methyl farnesoate (0.01%), β-Costol (0.02%). The in vivo anti-inflammatory activity was evaluated using the model of formol induced pate edema.